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If you're talking about a desktop or server version of Windows, then no, not in a very practical way. I'm not sure you'd want to anyway - as much as Windows can be useful on a desktop, it's not so prevalent in IoT gateways which are still resource-constrained to an extent, and have their own unique requirements. As an example, see here, type Ctrl-F to search for 'windows' - none of the mentioned gateways there are advertised to run a desktop or server version of Windows: https://www.postscapes.com/iot-gateways/
The OS resides on a Micro SD card, so you can just load another supported OS on another SD card and roll with that.
For Windows on a Raspberry Pi, you want to check out Windows IoT.
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Oh, wait, strike that. This is the IoT Gateway that has a 8GB eMMC flash memory, so good question.